Information for Healthcare Professionals

Genesis Serenity non-invasive prenatal test is an accurate screening option available from Genesis Genetics, experts in genetic testing. Serenity is…

  • Safe
    Routine, non-invasive maternal blood draw, just one tube (7–10 ml)
  • Accurate
    Very low failure rate (0.1%)
  • Fast
    Results reported less than 1 week after sample receipt.
  • Easy
    est as early as 10 weeks gestational age (8 weeks of foetal age as determined by date of conception). No limitations regarding ethnicity, BMI, ART or egg donor cases.

Genesis Serenity non-invasive prenatal test takes advantage of massively parallel sequencing to provide clearer resolution for reliable answers.

Superior technology—Strong clinical evidence showing across-the-genome analysis in a real-world population

Comprehensive analysis—uses peer reviewed statistical metrics with clinical outcome performance data on over 85,000 cases, surpassing any other test.

Informative results—Helpful classification reporting Aneuploidy detected or no aneuploidy detected. All DETECTED results must be followed with a diagnostic procedure such as amniocentesis or CVS.

Wide test options—Additional information on selected microdeletions and other aneuploidies (T9, T16) is also available upon request.

Serenity using Illumina NIPT technology Available Targeted Sequencing Tests
Definitive cut-off values provide clear screening results. Reporting Aneuploidy detected or No Aneuploidy detected Provides ambiguous risk scores similar to serum screens
Very low technical failure rate (0.1%) High failure rate (3-6% or greater)
Not constrained by BMI, ethnicity, or paternal sample May rely on BMI, ethnicity, or paternal sample to improve accuracy
Accepts egg donors Others may not

The basic Serenity NIPT screens for:

T21 (Down syndrome), T18 (Edwards syndrome), T13 (Patau syndrome)

And an option is available for sex chromosomes at no extra charge:

  • Monosomy X (MX; Turner syndrome)
  • XXX (Triple X)
  • XXY (Klinefelter syndrome)
  • XYY (Jacobs syndrome)
Foetal sex (XX or XY)—aids in stratifying the risk for X-linked disorders such as haemophilia, Duchenne muscular dystrophy, or cases of ambiguous genitalia, such as congenital adrenal hyperplasia.

The PLUS Serenity NIPT screens for:

The Basic test options as well as a panel of microdeletions currently includes 22q11 deletion (DiGeorge region), 15q11 deletion (Angelman/ Prader-Wili), 1p36 deletion, 4p (Wolf-Hirschorn), 5p (Cri-du Chat), chromosome trisomy 9 and 16.

*Additional cost and longer turnaround time (sent to Red Wood City Verinata/Illumina CLIA lab)